Dr. Wedge graduated from the University of Saskatchewan School of Medicine and, following a medical internship at Dalhousie University, completed her residency in Ophthalmology at the University of Toronto. After her one year clinical fellowship in Cornea and External Disease, also at the University of Toronto, she practiced at The Wellesley Hospital until its closure. She joined the Department of Ophthalmology at Michael Garron Hospital in 1999 and was named Chief in 2009. Dr. Wedge developed a Surgical Wet Lab teaching program for Ophthalmology residents to learn surgical skills and this program is now an integral part of the University of Toronto training program. In her role as Associate Medical Director of the Eye Bank of Canada, Ontario Division, Dr. Wedge collaborated with the Department of Obstetrics and Gynaecology at Michael Garron Hospital to start the first placental donation program to provide amniotic membrane for eye surgeries in hospitals across Ontario. The program received an Innovation Award from Michael Garron Hospital.